Wednesday, 21st May 2025
Arrival. Check-in to the Hotel.
Thursday, 22nd May 2025
Registration desk opens
OPENING REMARKS & INTRODUCTION
Chairs: Péter Vilmos and László Dux
Stefan Raunser | Keynote lecture
Structural insights into the function of actin and its interactions with friends and foes
Coffee break
ACTIN DYNAMICS - Session 1.
Chair: Beáta Bugyi
József Mihály
Actin regulatory proteins play a crucial role in radial growth of the sarcomeres in the Drosophila IFM
Laurent Blanchoin
Reconstituting the dynamic steady states of actin networks in vitro
Margot Quinlan
Using actin to put your head and heart in the right place
Beáta Bugyi
To see what everyone else has seen, and to think what nobody has thought
Lunch
ACTIN AND MECHANOTRANSDUCTION - Session 2.
Chair: Nils Gauthier
Lining Arnold Ju
Mechanosensing through F-actin reorganization
Robert Grosse
Nuclear actin mechano-properties during confined cell migration
Nils C. Gauthier
Ghostbusters: Catching spectrin skeleton in action
FLASH TALKS
Wouter Kools
Université Paris Cité, CNRS, Institut Jacques Monod, Paris, FranceMyosin-X bundles actin filaments and synchronizes barbed end growth
Shraman Kumar Bohra
University of Helsinki, Helsinki, FinlandArp2/3 regulates endothelial barrier integrity
Aurélie Favarin
Université Paris-Saclay, CEA, CNRS, Gif-sur-Yvette Cedex, FranceThe actomyosin-dependent α-catenin-vinculin-VASP machinery stimulates actin polymerisation
Coffee break
ACTIN IN DISEASES - Session 3.
Chair: Robert Grosse
Delphine Muriaux
Lipids and Cortical Actin in Virus Assembly
Mark P. Dodding
Composition and structure of filaments within the microtubule lumen.
Miklós Kellermayer
Molecular pathobiophysics of titin, a giant actin-binding muscle protein
Poster session I.
Welcome dinner
Friday, 23rd May 2025
Registration desk opens
ACTIN AND INTRACELLULAR TRAFFICKING - Session 4.
Chair: Noa Lamm-Shalem
David G. Drubin
Harnessing actin assembly forces for endocytic vesicle formation
Pekka Lappalainen
Assembly of functionally distinct actin filaments for cell adhesion and migration
Coffee break
Melina Schuh
New functions of actin in oocyte meiosis
Binyam Mogessie
Actin limits egg aneuploidies
FLASH TALKS
Sharof Khudayberdiev
Philipps-University of Marburg and Justus-Liebig-University, Giessen, Marburg, GermanyCAP1 acts as a cytosolic brake on MRTF-SRF signaling in neurons and the mouse brain
Jesse Hansen
Institute of Science and Technology Austria (ISTA), Klosterneuburg, AustriaStructure of the Huntingtin F-actin complex reveals its role in cytoskeleton organization
Archit Bhatnagar
Inst. of Biotechnology of the Czech Academy of Sciences, Vestec, Czech RepublicClathrin-mediated endocytosis associates with transient clusters of branched F-actin in the activated C. elegans oocyte
Lunch
ACTIN AND PHASE SEPARATION - Session 5.
Chair: Margot Quinlan
Yansong Miao
"EMBO Global Investigator Lecture
The scaffold protein Spa2 remodels ADP-actin upon energy starvation through phase separation
Jeanne C. Stachowiak
Protein condensates meet flexible substrates - actin filaments and membrane bilayers
Stephan W. Grill
Cortical condensate dynamics
Pavel Hozak
Nuclear phosphoinositides - New players in regulation of gene expression
Coffee break
FLASH TALKS
Marius Karger
Helmholtz Centre for Infection Research (HZI) and Technical University, Braunschweig, GermanyDifferential interference with actin-binding protein function by acute Cytochalasin B
Jonathan R. Gadsby
University of Cambridge, Cambridge, UKThe open to closed D-loop conformational switch determines length in filopodia-like actin bundles
Camille Bagès
Institut Jacques Monod, CNRS, Paris, FranceProbing actin-tropomyosin interactions with drag force
Poster session 2.
Evening Lecture - Women in Science
Katalin Karikó
2023 Nobel Prize laureate in physiology or medicine
DINNER
Saturday, 24th May 2025
Registration desk opens
ACTIN ACROSS EVOLUTION - Session 6.
Chair: Tina Tootle
Jan Löwe
Diverse cytomotive actins and tubulins share a polymerization switch mechanism conferring robust dynamics
Christa Schleper
A complex actin-based cytoskeleton predated the emergence of the first eukaryotes
Coffee break
Andrew J. Parnell
From cytoskeleton to colour how actin sculpts nanostructures responsible for structural colour in butterfly wings
Noriko Inada
How do actin filaments regulate plant physiologies?
FLASH TALKS
Nikki Nafar
Delft University of Technology, Delft, NetherlandsDecoupling the Actin Cortex’s Role in Membrane Electroporation
Md Hasanuzzaman
Center for Integrative Infectious Disease Research, Heidelberg University, Heidelberg, GermanyConservation of ArpC5L-mediated Nuclear Actin Polymerization in Immune Cells
Valentina Fambri
New York University Abu Dhabi, Abu Dhabi, UAEThe Role of Nuclear Myosin 1 in Mouse Brain Development
Lunch
Poster session 3.
ACTIN AND THE GENOME - Session 7.
Chair: Piergiorgio Percipalle
Karl-Peter Hopfner
Roles of nuclear actin and actin related proteins in chromatin remodeling
Tina Tootle
Prostaglandins and Fascin regulate nuclear actin to control nucleolar function
Noa Lamm-Shalem
Nuclear F-actin in replication stress response
Péter Vilmos
Complex regulation of the nuclear localization of an actin-binding protein
Closing Remarks
Bridge fair and wine festival in Szeged
Sunday, 25th May 2025
Check-out from the Hotel, Departure
List of Posters
Probing actin-tropomyosin interactions with drag force
Camille Bagès
Clathrin-mediated endocytosis associates with transient clusters of branched F-actin in the activated C. elegans oocyte
Archit Bhatnagar
Arp2/3 in Endothelial Barrier Integrity
Shraman Kumar Bohra
The Role of Nuclear Myosin 1 in Mouse Brain Development
Valentina Fambri
The actomyosin-dependent α-catenin-vinculin-VASP machinery stimulates actin polymerisation
Aurélie Favarin
The open to closed D-loop conformational switch determines length in filopodia-like actin bundles
Jonathan Gadsby
Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton organization
Jesse Hansen
Conservation of ArpC5L-mediated Nuclear Actin Polymerization in Immune Cells
Md Hasanuzzaman
Differential interference with actin-binding protein function by acute Cytochalasin B
Marius Karger
CAP1 acts as a cytosolic brake on MRTF-SRF signaling in neurons and the mouse brain
Sharof Khudayberdiev
Myosin-X bundles actin filaments and synchronizes barbed end growth
Wouter Kools
Decoupling the Actin Cortex’s Role in Membrane Electroporation
Nikki Nafar
Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly
Micaela Boiero Sanders
The Role of the Actin Cortex in DNA Electrotransfer
Sophie de Boer
Deciphering actin-riched podosome stabilization in immune cell accumulation on surface nanotopography
Zihui Fan
EB1: Structural dynamics and aggregation
Péter Gaszler
Flightless-I and Drosophila LRRFIP2 work together to regulate radial growth of the sarcomeres
Péter Görög
Nuclear actin-dependent Meg3 expression suppresses metabolic genes by affecting the chromatin architecture at sites of elevated H3K27 acetylation levels
Nadine Hosny El Said
Endothelial-mesenchymal transition and possible role of cytokines in streptozotocin induced diabetic heart
Lin Hsu
Large-scale imaging of cellular actin networks at single filament resolution using cryo-ET
Manjunath Javoor
Signal-regulated clustering of nuclear myosin vi at the androgen receptor promotes transcription
Irma Jayawardana
Mechano-induced nuclear rupture triggers nuclear actin polymerization to limit chromatin leakage in migrating cancer cells
Christos Kamaras
Novel assays determine optimal conditions for actin turnover in cell-like conditions
Fabina Binth Kandiyoth
Nuclear Myosin 1-driven transcriptional reprogramming in adipogenesis regulates obesity in mice
Samira Khalaji
Breaking Hearts: FHOD3 HCM mutations disrupt cardiac sarcomere formation
Angela Koeberlein
Stress fiber architecture, cell migration and morphogenesis are controlled by calponin-family proteins in an isoform-specific manner
Shrikant Kokate
The nuclear import of the actin-binding moesin protein is regulated by cytoplasmic retention
Zoltán Kovács
The roles of Arabidopsis thaliana actin filaments in the regulation of chromatin organization
Tomoko Matsumoto
Molecular mechanism of actin filament elongation by formins
Wout Oosterheert
Nuclear Actin: Shaping genome and sensing forces
Piergiorgio Percipalle
Efficient migration of toxoplasma gondii-infected dendritic cells is driven by host actin-myosin network and parasite mechanical resilience
Francisco Periz
Exploring the localization and dynamics of the actin Cytoskeleton in Ca. Lokiarchaeum ossiferum
Philipp Radler
BORG3 controls septin polymerization for primary cilia formation
Janik Niklas Schampera
Disordered region in an actin-binding protein regulates its nuclear import
Anikó Szabó
CP/V-1 Antagonism governs muscle hypertrophy by regulating the number of myofilaments
Szilárd Szikora
SPEEDFix: Rapid fixation of migrating cells for network analysis
Kain van den Elsen
Structure-function coordination in the sals protein
Andrea Vig
Selective recruitment of tropomyosin isoforms to actin filaments
Hugo Wioland
Topographical Cues Orchestrate Actin Nucleation via N-WASP–FBP17 Nano-condensation
Kexin Zhu
Czech-BioImaging: Infrastructure Dedicated to Users for 10 Years
Pavel Hozak
The impact of toxofilin69-196 fragment on the disassembly of actin
Veronika Takács-Kollár
Structural insight into small-molecule resistance in profilin and actin mutant malaria parasites
Jude Santhampillai
The solenoid protein GAC provides momentum for the actin-myosin motor in Apicomplexa
Isa Pires
Identification of novel importins responsible for the nuclear transport of actin
Péter Borkúti
Evolution of actin assembly in endocytosis via WDS proteins
VT Bagyashree